Wybrane publikacje
Wybrane publikacje
- Cabanes-Creus M, Navarro RG, Liao SHY, Scott S, Carlessi R, Roca-Pinilla R, Knight M, Baltazar G, Zhu E, Jones M, Denisenko E, Forrest ARR, Alexander IE, Tirnitz-Parker JEE, Lisowski L. Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution. Mol Ther Methods Clin Dev. 2023 Jan 2;28:220-237. doi: 10.1016/j.omtm.2022.12.014. PMID: 36700121; PMCID: PMC9860073.
- Westhaus A, Cabanes-Creus M, Jonker T, Sallard E, Navarro RG, Zhu E, Baltazar Torres G, Lee S, Wilmott P, Gonzalez-Cordero A, Santilli G, Thrasher AJ, Alexander IE, Lisowski L. AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression. Hum Gene Ther. 2022 Jun;33(11-12):664-682. doi: 10.1089/hum.2021.278. Epub 2022 May 6. PMID: 35297686.
- Chen J, Zhao Y, Zhang F, Li J, Boland JA, Cheng NC, Liu K, Tiffen JC, Bertolino P, Bowen DG, Krueger A, Lisowski L, Alexander IE, Vadas MA, El-Omar E, Gamble JR, McCaughan GW. Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7. Cell Mol Life Sci. 2022 Jul 22;79(8):443. doi: 10.1007/s00018-022-04452-6. PMID: 35867177; PMCID: PMC9307539.
- Cabanes-Creus M, Navarro RG, Zhu E, Baltazar G, Liao SHY, Drouyer M, Amaya AK, Scott S, Nguyen LH, Westhaus A, Hebben M, Wilson LOW, Thrasher AJ, Alexander IE, Lisowski L. Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8. Mol Ther Methods Clin Dev. 2021 Nov 25;24:88-101. doi: 10.1016/j.omtm.2021.11.011. PMID: 34977275; PMCID: PMC8693155.
- Too LK, Shen W, Protti DA, Sawatari A, A Black D, Leamey CA, Y Huang J, Lee SR, E Mathai A, Lisowski L, Y Lin J, C Gillies M, Simunovic MP. Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin. Sci Rep. 2022 Nov 11;12(1):19312. doi: 10.1038/s41598-022-23572-4. PMID: 36369267; PMCID: PMC9652428.
- Blazev R, Carl CS, Ng YK, Molendijk J, Voldstedlund CT, Zhao Y, Xiao D, Kueh AJ, Miotto PM, Haynes VR, Hardee JP, Chung JD, McNamara JW, Qian H, Gregorevic P, Oakhill JS, Herold MJ, Jensen TE, Lisowski L, Lynch GS, Dodd GT, Watt MJ, Yang P, Kiens B, Richter EA, Parker BL. Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function. Cell Metab. 2022 Oct 4;34(10):1561-1577.e9. doi: 10.1016/j.cmet.2022.07.003. Epub 2022 Jul 25. PMID: 35882232.
- Roca-Pinilla R, Lisowski L, Arís A, Garcia-Fruitós E. The future of recombinant host defense peptides. Microb Cell Fact. 2022 Dec 21;21(1):267. doi: 10.1186/s12934-022-01991-2. PMID: 36544150; PMCID: PMC9768982.
- Banne E, Abudiab B, Abu-Swai S, Repudi SR, Steinberg DJ, Shatleh D, Alshammery S, Lisowski L, Gold W, Carlen PL, Aqeilan RI. Neurological Disorders Associated with WWOX Germline Mutations-A Comprehensive Overview. Cells. 2021 Apr 7;10(4):824. doi: 10.3390/cells10040824. PMID: 33916893; PMCID: PMC8067556.
- Baruteau J, Cunningham SC, Yilmaz BS, Perocheau DP, Eaglestone S, Burke D, Thrasher AJ, Waddington SN, Lisowski L, Alexander IE, Gissen P. Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys. Mol Ther Methods Clin Dev. 2021 Sep 14;23:135-146. doi: 10.1016/j.omtm.2021.09.005. PMID: 34703837; PMCID: PMC8517016.
- Zammit NW, Seeberger KL, Zamerli J, Walters SN, Lisowski L, Korbutt GS, Grey ST. Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation. Xenotransplantation. 2021 May;28(3):e12669. doi: 10.1111/xen.12669. Epub 2020 Dec 14. PMID: 33316848.
- Cabanes-Creus M, Navarro RG, Liao SHY, Baltazar G, Drouyer M, Zhu E, Scott S, Luong C, Wilson LOW, Alexander IE, Lisowski L. Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids. Mol Ther Methods Clin Dev. 2021 Apr 24;21:607-620. doi: 10.1016/j.omtm.2021.04.010. PMID: 34095344; PMCID: PMC8142051.
- Lisowski L, Staber JM, Wright JF, Valentino LA. The intersection of vector biology, gene therapy, and hemophilia. Res Pract Thromb Haemost. 2021 Sep 1;5(6):e12586. doi: 10.1002/rth2.12586. PMID: 34485808; PMCID: PMC8410952.
- Son ET, Faridi P, Paul-Heng M, Leong ML, English K, Ramarathinam SH, Braun A, Dudek NL, Alexander IE, Lisowski L, Bertolino P, Bowen DG, Purcell AW, Mifsud NA, Sharland AF. The self-peptide repertoire plays a critical role in transplant tolerance induction. J Clin Invest. 2021 Nov 1;131(21):e146771. doi: 10.1172/JCI146771. PMID: 34428180; PMCID: PMC8553557.